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High Soluble Amyloid-β(42) Predicts Normal Cognition in Amyloid-Positive Individuals with Alzheimer’s Disease-Causing Mutations

BACKGROUND: In amyloid-positive individuals at risk for Alzheimer’s disease (AD), high soluble 42-amino acid amyloid-β (Aβ(42)) levels are associated with normal cognition. It is unknown if this relationship applies longitudinally in a genetic cohort. OBJECTIVE: To test the hypothesis that high Aβ(4...

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Detalles Bibliográficos
Autores principales:	Sturchio, Andrea, Dwivedi, Alok K., Malm, Tarja, Wood, Matthew J.A., Cilia, Roberto, Sharma, Jennifer S., Hill, Emily J., Schneider, Lon S., Graff-Radford, Neill R., Mori, Hiroshi, Nübling, Georg, El Andaloussi, Samir, Svenningsson, Per, Ezzat, Kariem, Espay, Alberto J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661329/ https://www.ncbi.nlm.nih.gov/pubmed/36120786 http://dx.doi.org/10.3233/JAD-220808

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