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Mortality in hospitalized HIV-infected patients in a referral center in Bahia, Brazil

The number of people living with HIV / AIDS in the world has increased and, in Salvador, Brazil, the mortality rate is above the state and national rates. This study sought to describe the characteristics of HIV patients who died in a referral hospital. This is a retrospective cohort study between 2...

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Autores principales: Nascimento, Luca, Improta-Caria, Alex Cleber, Brites, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661378/
https://www.ncbi.nlm.nih.gov/pubmed/36356643
http://dx.doi.org/10.1016/j.bjid.2022.102716
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author Nascimento, Luca
Improta-Caria, Alex Cleber
Brites, Carlos
author_facet Nascimento, Luca
Improta-Caria, Alex Cleber
Brites, Carlos
author_sort Nascimento, Luca
collection PubMed
description The number of people living with HIV / AIDS in the world has increased and, in Salvador, Brazil, the mortality rate is above the state and national rates. This study sought to describe the characteristics of HIV patients who died in a referral hospital. This is a retrospective cohort study between 2012 and 2017 conducted at the, Federal University of Bahia´s Hospital, involving patients who died during hospitalization. There were 62 deaths among the 461 hospitalized patients with a predominance of males, blacks, and residents of Salvador. Mean age was 41.4 years. Most patients had at least one associated infection and 13% had a malignant neoplasm. The main reported cause of death was septic shock / HIV-associated infections. About 6.4% had an undetectable viral load and in-hospital survival was longer in this group. The lowest in-hospital survival was seen in patients presenting with pneumonia. Although the HIV / AIDS mortality rate at this center reflects the complexity of the country's epidemiological scenario poor adherence and therapeutic failure play a key role in the risk of death.
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spelling pubmed-96613782022-11-15 Mortality in hospitalized HIV-infected patients in a referral center in Bahia, Brazil Nascimento, Luca Improta-Caria, Alex Cleber Brites, Carlos Braz J Infect Dis Brief Communication The number of people living with HIV / AIDS in the world has increased and, in Salvador, Brazil, the mortality rate is above the state and national rates. This study sought to describe the characteristics of HIV patients who died in a referral hospital. This is a retrospective cohort study between 2012 and 2017 conducted at the, Federal University of Bahia´s Hospital, involving patients who died during hospitalization. There were 62 deaths among the 461 hospitalized patients with a predominance of males, blacks, and residents of Salvador. Mean age was 41.4 years. Most patients had at least one associated infection and 13% had a malignant neoplasm. The main reported cause of death was septic shock / HIV-associated infections. About 6.4% had an undetectable viral load and in-hospital survival was longer in this group. The lowest in-hospital survival was seen in patients presenting with pneumonia. Although the HIV / AIDS mortality rate at this center reflects the complexity of the country's epidemiological scenario poor adherence and therapeutic failure play a key role in the risk of death. Elsevier 2022-11-07 /pmc/articles/PMC9661378/ /pubmed/36356643 http://dx.doi.org/10.1016/j.bjid.2022.102716 Text en © 2022 Sociedade Brasileira de Infectologia. Published by Elsevier España, S.L.U. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Brief Communication
Nascimento, Luca
Improta-Caria, Alex Cleber
Brites, Carlos
Mortality in hospitalized HIV-infected patients in a referral center in Bahia, Brazil
title Mortality in hospitalized HIV-infected patients in a referral center in Bahia, Brazil
title_full Mortality in hospitalized HIV-infected patients in a referral center in Bahia, Brazil
title_fullStr Mortality in hospitalized HIV-infected patients in a referral center in Bahia, Brazil
title_full_unstemmed Mortality in hospitalized HIV-infected patients in a referral center in Bahia, Brazil
title_short Mortality in hospitalized HIV-infected patients in a referral center in Bahia, Brazil
title_sort mortality in hospitalized hiv-infected patients in a referral center in bahia, brazil
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661378/
https://www.ncbi.nlm.nih.gov/pubmed/36356643
http://dx.doi.org/10.1016/j.bjid.2022.102716
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