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Porcn is essential for growth and invagination of the mammalian optic cup
Microphthalmia, anophthalmia, and coloboma (MAC) are congenital ocular malformations causing 25% of childhood blindness. The X-linked disorder Focal Dermal Hypoplasia (FDH) is frequently associated with MAC and results from mutations in Porcn, a membrane bound O-acyl transferase required for palmito...
Autores principales: | Fuhrmann, Sabine, Ramirez, Sara, Mina Abouda, Mirna, Campbell, Clorissa D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661423/ https://www.ncbi.nlm.nih.gov/pubmed/36393832 http://dx.doi.org/10.3389/fcell.2022.1016182 |
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