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Contextual Validation of the Prediction of Postoperative Complications of Colorectal Surgery by the “ACS NSQIP(®) Risk Calculator” in a Tunisian Center
CONTEXT: Models for predicting individual risks of surgical complications are advantageous for operative decision making and the nature of postoperative management procedures. OBJECTIVE: Validate the “ACS NSQIP(®) Risk Calculator” in the prediction of postoperative complications during colorectal ca...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661577/ https://www.ncbi.nlm.nih.gov/pubmed/36386277 http://dx.doi.org/10.1177/11769351221135153 |
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author | Ben Abdelkrim, Mehdi Elghali, Mohamed Amine Moussa, Amany Ben Abdelaziz, Ahmed |
author_facet | Ben Abdelkrim, Mehdi Elghali, Mohamed Amine Moussa, Amany Ben Abdelaziz, Ahmed |
author_sort | Ben Abdelkrim, Mehdi |
collection | PubMed |
description | CONTEXT: Models for predicting individual risks of surgical complications are advantageous for operative decision making and the nature of postoperative management procedures. OBJECTIVE: Validate the “ACS NSQIP(®) Risk Calculator” in the prediction of postoperative complications during colorectal cancer surgery, operated during the years 2015 to 2019. METHODS: this is a prognostic validation study of the “ACS NSQIP(®)” applied retrospectively to patients operated on for colorectal cancer in the surgical department of Farhat Hached hospital, during the 2015 and 2019 5-year term. Three levels of adjustment. Discrimination and calibration were carried out mainly by ROC curves (AUC ⩾ 0.8). RESULTS: In this study, 129 patients were included with a sex ratio of 1.22 and a median age of 62 years. The most common operative procedure was low segmental colectomy with colorectal anastomosis. Thirty-seven patients (28.7%) had at least one postoperative complication. The prediction and cuts-off points values of mortality (AUC = 0.858; CI(95%) [0.570-0.960]; Cuts-off points = 1.8%), cardiac complications (AUC = 0.824; CI(95%) [0.658-0.990]; Cuts-off points = 1.8%), thromboembolic complications (AUC = 0.802; CI(95%) [0.617-0.987]; Cuts-off point = 3.1%), and renal insufficiency (AUC = 0.802; CI(95%) [ 0.623-0.981]; Cuts-off point = 1.2%) were adjusted according to level 1 of the calculator. CONCLUSION: This work contextualized the prediction of postoperative complications in colorectal surgery in the university general surgery department of Farhat Hached in Sousse (Tunisia), making it possible to improve the quality and safety of surgical care. The application of the Tunisian mini calculator is recommended as well as the generalization of validation following the development of a generic calculator for all operating procedures. |
format | Online Article Text |
id | pubmed-9661577 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-96615772022-11-15 Contextual Validation of the Prediction of Postoperative Complications of Colorectal Surgery by the “ACS NSQIP(®) Risk Calculator” in a Tunisian Center Ben Abdelkrim, Mehdi Elghali, Mohamed Amine Moussa, Amany Ben Abdelaziz, Ahmed Cancer Inform Original Research CONTEXT: Models for predicting individual risks of surgical complications are advantageous for operative decision making and the nature of postoperative management procedures. OBJECTIVE: Validate the “ACS NSQIP(®) Risk Calculator” in the prediction of postoperative complications during colorectal cancer surgery, operated during the years 2015 to 2019. METHODS: this is a prognostic validation study of the “ACS NSQIP(®)” applied retrospectively to patients operated on for colorectal cancer in the surgical department of Farhat Hached hospital, during the 2015 and 2019 5-year term. Three levels of adjustment. Discrimination and calibration were carried out mainly by ROC curves (AUC ⩾ 0.8). RESULTS: In this study, 129 patients were included with a sex ratio of 1.22 and a median age of 62 years. The most common operative procedure was low segmental colectomy with colorectal anastomosis. Thirty-seven patients (28.7%) had at least one postoperative complication. The prediction and cuts-off points values of mortality (AUC = 0.858; CI(95%) [0.570-0.960]; Cuts-off points = 1.8%), cardiac complications (AUC = 0.824; CI(95%) [0.658-0.990]; Cuts-off points = 1.8%), thromboembolic complications (AUC = 0.802; CI(95%) [0.617-0.987]; Cuts-off point = 3.1%), and renal insufficiency (AUC = 0.802; CI(95%) [ 0.623-0.981]; Cuts-off point = 1.2%) were adjusted according to level 1 of the calculator. CONCLUSION: This work contextualized the prediction of postoperative complications in colorectal surgery in the university general surgery department of Farhat Hached in Sousse (Tunisia), making it possible to improve the quality and safety of surgical care. The application of the Tunisian mini calculator is recommended as well as the generalization of validation following the development of a generic calculator for all operating procedures. SAGE Publications 2022-11-10 /pmc/articles/PMC9661577/ /pubmed/36386277 http://dx.doi.org/10.1177/11769351221135153 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Research Ben Abdelkrim, Mehdi Elghali, Mohamed Amine Moussa, Amany Ben Abdelaziz, Ahmed Contextual Validation of the Prediction of Postoperative Complications of Colorectal Surgery by the “ACS NSQIP(®) Risk Calculator” in a Tunisian Center |
title | Contextual Validation of the Prediction of Postoperative Complications of Colorectal Surgery by the “ACS NSQIP(®)
Risk Calculator” in a Tunisian Center |
title_full | Contextual Validation of the Prediction of Postoperative Complications of Colorectal Surgery by the “ACS NSQIP(®)
Risk Calculator” in a Tunisian Center |
title_fullStr | Contextual Validation of the Prediction of Postoperative Complications of Colorectal Surgery by the “ACS NSQIP(®)
Risk Calculator” in a Tunisian Center |
title_full_unstemmed | Contextual Validation of the Prediction of Postoperative Complications of Colorectal Surgery by the “ACS NSQIP(®)
Risk Calculator” in a Tunisian Center |
title_short | Contextual Validation of the Prediction of Postoperative Complications of Colorectal Surgery by the “ACS NSQIP(®)
Risk Calculator” in a Tunisian Center |
title_sort | contextual validation of the prediction of postoperative complications of colorectal surgery by the “acs nsqip(®)
risk calculator” in a tunisian center |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661577/ https://www.ncbi.nlm.nih.gov/pubmed/36386277 http://dx.doi.org/10.1177/11769351221135153 |
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