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Discovery of novel inhibitors of ghrelin O-acyltransferase enzyme: an in-silico approach

BACKGROUND AND PURPOSE: Ghrelin is known as a hunger hormone and plays a pivotal role in appetite, food intake, energy balance, glucose metabolism, and insulin secretion, making it a potential target for the treatment of obesity and type 2 diabetes. The essential maturation step of ghrelin to activa...

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Detalles Bibliográficos
Autores principales:	Hosseini, Faezeh Sadat, Ghassempour, Alireza, Amanlou, Massoud
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer - Medknow 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661681/ https://www.ncbi.nlm.nih.gov/pubmed/36386482 http://dx.doi.org/10.4103/1735-5362.355212

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