Identification of Inhibitors of the Schistosoma mansoni VKR2 Kinase Domain

[Image: see text] Schistosomiasis is a neglected tropical disease caused by parasitic flatworms. Current treatment relies on just one partially effective drug, praziquantel (PZQ). Schistosoma mansoni Venus Kinase Receptors 1 and 2 (SmVKR1 and SmVKR2) are important for parasite growth and egg product...

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Detalles Bibliográficos
Autores principales: Mathavan, Indran, Liu, Lawrence J., Robinson, Sean W., El-Sakkary, Nelly, Elatico, Adam Jo J., Gomez, Darwin, Nellas, Ricky, Owens, Raymond J., Zuercher, William, Navratilova, Iva, Caffrey, Conor R., Beis, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661718/
https://www.ncbi.nlm.nih.gov/pubmed/36385939
http://dx.doi.org/10.1021/acsmedchemlett.2c00248

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