Human targeted phenobarbital presents a poor substrate of gut microbiome deciphering new drug targets beyond pharmacokinetic curbs

BACKGROUND: The gut microbiome, a new organ of the body, can potentially alter the pharmacokinetics of orally administered drugs through microbial enzymes. However, absorption of orally administered non-antibiotic drugs by the gut microbiome, during drug-microbiome interaction, is barely addressed....

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Detalles Bibliográficos
Autores principales: Mukhtar, Imran, Anwar, Haseeb, Iftikhar, Arslan, Hashem, Heba E., Ali, Qasim, Siddique, Farhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661781/
https://www.ncbi.nlm.nih.gov/pubmed/36376913
http://dx.doi.org/10.1186/s40360-022-00618-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661781/
https://www.ncbi.nlm.nih.gov/pubmed/36376913
http://dx.doi.org/10.1186/s40360-022-00618-x

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