Optimal target of LDL cholesterol level for statin treatment: challenges to monotonic relationship with cardiovascular events

BACKGROUND: Aggressive lipid lowering by high-dose statin treatment has been established for the secondary prevention of coronary artery disease (CAD). Regarding the low-density lipoprotein cholesterol (LDL-C) level, however, the “The lower is the better” concept has been controversial to date. We h...

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Detalles Bibliográficos
Autores principales: Sakuma, Masashi, Iimuro, Satoshi, Shinozaki, Tomohiro, Kimura, Takeshi, Nakagawa, Yoshihisa, Ozaki, Yukio, Iwata, Hiroshi, Miyauchi, Katsumi, Daida, Hiroyuki, Suwa, Satoru, Sakuma, Ichiro, Nishihata, Yosuke, Saito, Yasushi, Ogawa, Hisao, Matsuzaki, Masunori, Ohashi, Yasuo, Taguchi, Isao, Toyoda, Shigeru, Inoue, Teruo, Nagai, Ryozo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661797/
https://www.ncbi.nlm.nih.gov/pubmed/36372869
http://dx.doi.org/10.1186/s12916-022-02633-5

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