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MEDICC2: whole-genome doubling aware copy-number phylogenies for cancer evolution

Aneuploidy, chromosomal instability, somatic copy-number alterations, and whole-genome doubling (WGD) play key roles in cancer evolution and provide information for the complex task of phylogenetic inference. We present MEDICC2, a method for inferring evolutionary trees and WGD using haplotype-speci...

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Detalles Bibliográficos
Autores principales:	Kaufmann, Tom L., Petkovic, Marina, Watkins, Thomas B. K., Colliver, Emma C., Laskina, Sofya, Thapa, Nisha, Minussi, Darlan C., Navin, Nicholas, Swanton, Charles, Van Loo, Peter, Haase, Kerstin, Tarabichi, Maxime, Schwarz, Roland F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661799/ https://www.ncbi.nlm.nih.gov/pubmed/36376909 http://dx.doi.org/10.1186/s13059-022-02794-9

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