Differential Oral Microbial Input Determines Two Microbiota Pneumo‐Types Associated with Health Status (Adv. Sci. 32/2022)

Lung Microbiota The lungs were previously considered sterile, however high‐throughput metagenomic sequencing of bronchia‐alveolar lavage fluid samples has identified the presence of commensal microorganisms. In article number 2203115, Jingxiang Zhang, Guo‐Bao Tian, Tao Ding, and co‐workers have found that differential input from oral bacteria determines the specific composition of the lung microbiota. They identified two different microbiota pneumo‐types and found that a high oral input type of lung microbiota was associated with higher levels of inflammatory cytokines and poorer clinical indices. This study again calls our attention to the impact of oral microbiota on human respiratory health. [Image: see text]