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Implantable Electroceutical Approach Improves Myelination by Restoring Membrane Integrity in a Mouse Model of Peripheral Demyelinating Neuropathy (Adv. Sci. 32/2022)
Charcot‐Marie‐Tooth Disease Charcot‐Marie‐Tooth (CMT) disease – the most prevalent inherited peripheral neuropathy worldwide – currently lacks an approved treatment, as the biochemical interventions attempted have remained unsuccessful. In article number 2201358, Minseok S. Kim and co‐workers introd...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661863/ http://dx.doi.org/10.1002/advs.202270208 |
| _version_ | 1784830568011137024 |
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| author | Intisar, Aseer Shin, Hyun Young Kim, Woon‐Hae Kang, Hyun Gyu Kim, Min Young Kim, Yu Seon Cho, Youngjun Mo, Yun Jeoung Lim, Heejin Lee, Sanghoon Lu, Q. Richard Lee, Yun‐Il Kim, Minseok S. |
| author_facet | Intisar, Aseer Shin, Hyun Young Kim, Woon‐Hae Kang, Hyun Gyu Kim, Min Young Kim, Yu Seon Cho, Youngjun Mo, Yun Jeoung Lim, Heejin Lee, Sanghoon Lu, Q. Richard Lee, Yun‐Il Kim, Minseok S. |
| author_sort | Intisar, Aseer |
| collection | PubMed |
| description | Charcot‐Marie‐Tooth Disease Charcot‐Marie‐Tooth (CMT) disease – the most prevalent inherited peripheral neuropathy worldwide – currently lacks an approved treatment, as the biochemical interventions attempted have remained unsuccessful. In article number 2201358, Minseok S. Kim and co‐workers introduce a paradigm‐shifting biophysical treatment for CMT disease based on electroceuticals. The optimal electrical stimulation condition improves peripheral myelination by inducing a dynamic recovery in the distribution of key biomolecular constituents of myelin, thus restoring the myelin membrane integrity. [Image: see text] |
| format | Online Article Text |
| id | pubmed-9661863 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | John Wiley and Sons Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-96618632022-11-14 Implantable Electroceutical Approach Improves Myelination by Restoring Membrane Integrity in a Mouse Model of Peripheral Demyelinating Neuropathy (Adv. Sci. 32/2022) Intisar, Aseer Shin, Hyun Young Kim, Woon‐Hae Kang, Hyun Gyu Kim, Min Young Kim, Yu Seon Cho, Youngjun Mo, Yun Jeoung Lim, Heejin Lee, Sanghoon Lu, Q. Richard Lee, Yun‐Il Kim, Minseok S. Adv Sci (Weinh) Back Cover Charcot‐Marie‐Tooth Disease Charcot‐Marie‐Tooth (CMT) disease – the most prevalent inherited peripheral neuropathy worldwide – currently lacks an approved treatment, as the biochemical interventions attempted have remained unsuccessful. In article number 2201358, Minseok S. Kim and co‐workers introduce a paradigm‐shifting biophysical treatment for CMT disease based on electroceuticals. The optimal electrical stimulation condition improves peripheral myelination by inducing a dynamic recovery in the distribution of key biomolecular constituents of myelin, thus restoring the myelin membrane integrity. [Image: see text] John Wiley and Sons Inc. 2022-11-14 /pmc/articles/PMC9661863/ http://dx.doi.org/10.1002/advs.202270208 Text en © 2022 Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
| spellingShingle | Back Cover Intisar, Aseer Shin, Hyun Young Kim, Woon‐Hae Kang, Hyun Gyu Kim, Min Young Kim, Yu Seon Cho, Youngjun Mo, Yun Jeoung Lim, Heejin Lee, Sanghoon Lu, Q. Richard Lee, Yun‐Il Kim, Minseok S. Implantable Electroceutical Approach Improves Myelination by Restoring Membrane Integrity in a Mouse Model of Peripheral Demyelinating Neuropathy (Adv. Sci. 32/2022) |
| title | Implantable Electroceutical Approach Improves Myelination by Restoring Membrane Integrity in a Mouse Model of Peripheral Demyelinating Neuropathy (Adv. Sci. 32/2022) |
| title_full | Implantable Electroceutical Approach Improves Myelination by Restoring Membrane Integrity in a Mouse Model of Peripheral Demyelinating Neuropathy (Adv. Sci. 32/2022) |
| title_fullStr | Implantable Electroceutical Approach Improves Myelination by Restoring Membrane Integrity in a Mouse Model of Peripheral Demyelinating Neuropathy (Adv. Sci. 32/2022) |
| title_full_unstemmed | Implantable Electroceutical Approach Improves Myelination by Restoring Membrane Integrity in a Mouse Model of Peripheral Demyelinating Neuropathy (Adv. Sci. 32/2022) |
| title_short | Implantable Electroceutical Approach Improves Myelination by Restoring Membrane Integrity in a Mouse Model of Peripheral Demyelinating Neuropathy (Adv. Sci. 32/2022) |
| title_sort | implantable electroceutical approach improves myelination by restoring membrane integrity in a mouse model of peripheral demyelinating neuropathy (adv. sci. 32/2022) |
| topic | Back Cover |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661863/ http://dx.doi.org/10.1002/advs.202270208 |
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