Caffeine reduces oxidative stress to protect against hyperoxia-induced lung injury via the adenosine A2A receptor/cAMP/PKA/Src/ERK1/2/p38MAPK pathway

Objectives: Caffeine has been shown to reduce the incidence of bronchopulmonary dysplasia (BPD). To investigate the protective mechanism of caffeine in a hyperoxia-based cell model of BPD in vitro. Methods: Type II alveolar epithelial cells (AECs II) were isolated and randomly divided into 6 groups:...

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Detalles Bibliográficos
Autores principales: Wang, Xijuan, Lv, Shuai, Sun, Jianwei, Zhang, Meihui, Zhang, Lei, Sun, Yan, Zhao, Ziyan, Wang, Dandan, Zhao, Xinjing, Zhang, Jiajie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662006/
https://www.ncbi.nlm.nih.gov/pubmed/36357965
http://dx.doi.org/10.1080/13510002.2022.2143114

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