Cardiac PI3K p110α attenuation delays aging and extends lifespan

Phosphoinositide 3-kinase (PI3K) is a key component of the insulin signaling pathway that controls cellular me-tabolism and growth. Loss-of-function mutations in PI3K signaling and other downstream effectors of the insulin signaling pathway extend the lifespan of various model organisms. However, th...

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Detalles Bibliográficos
Autores principales: Abdellatif, Mahmoud, Eisenberg, Tobias, Heberle, Alexander Martin, Thedieck, Kathrin, Kroemer, Guido, Sedej, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2022
Materias:
News and Thoughts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662025/
https://www.ncbi.nlm.nih.gov/pubmed/36447531
http://dx.doi.org/10.15698/cst2022.08.270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662025/
https://www.ncbi.nlm.nih.gov/pubmed/36447531
http://dx.doi.org/10.15698/cst2022.08.270

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