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Cardiac PI3K p110α attenuation delays aging and extends lifespan
Phosphoinositide 3-kinase (PI3K) is a key component of the insulin signaling pathway that controls cellular me-tabolism and growth. Loss-of-function mutations in PI3K signaling and other downstream effectors of the insulin signaling pathway extend the lifespan of various model organisms. However, th...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Shared Science Publishers OG
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662025/ https://www.ncbi.nlm.nih.gov/pubmed/36447531 http://dx.doi.org/10.15698/cst2022.08.270 |