Tuberous Sclerosis Complex 1 Deficiency in Macrophages Promotes Unclassical Inflammatory Response to Lipopolysaccharide In Vitro and Dextran Sodium Sulfate-Induced Colitis in Mice

Human tuberous sclerosis (TSC) is mainly caused by genetic mutations of tuberous TSC1or TSC2. Recent studies found that TSC1 deficiency promoted classical M1 macrophage polarization. However, whether TSC1 regulates other inflammatory cytokine expression in lipopolysaccharidem (LPS)-stimulated macrop...

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Detalles Bibliográficos
Autores principales: Xu, Huawen, Zhao, Yang, Zhao, Qingjie, Shi, Mingpu, Zhang, Zhaoqi, Ding, Wenjun, Zhao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662278/
https://www.ncbi.nlm.nih.gov/pubmed/36465179
http://dx.doi.org/10.14336/AD.2022.0408

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