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Rapid Recovery of Acute Respiratory Distress Syndrome in Scrub Typhus, With Pulse Methylprednisolone and Therapeutic Plasma Exchange

Acute respiratory distress syndrome (ARDS) is an atypical presentation of scrub typhus infection with associated high morbidity and mortality compared to uncomplicated scrub typhus infection. Here we report an otherwise healthy 41-year-old female patient admitted with moderate ARDS secondary to scru...

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Autores principales: Rathnasekara, Thilina, Wijekoon, Lanka, Senanayake, Hemal, Siribaddana, Sisira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662697/
https://www.ncbi.nlm.nih.gov/pubmed/36407237
http://dx.doi.org/10.7759/cureus.30329
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author Rathnasekara, Thilina
Wijekoon, Lanka
Senanayake, Hemal
Siribaddana, Sisira
author_facet Rathnasekara, Thilina
Wijekoon, Lanka
Senanayake, Hemal
Siribaddana, Sisira
author_sort Rathnasekara, Thilina
collection PubMed
description Acute respiratory distress syndrome (ARDS) is an atypical presentation of scrub typhus infection with associated high morbidity and mortality compared to uncomplicated scrub typhus infection. Here we report an otherwise healthy 41-year-old female patient admitted with moderate ARDS secondary to scrub typhus infection who gained comparatively rapid recovery within 72 hours following intravenous methylprednisolone pulse (MPP) therapy with therapeutic plasma exchange (TPE), suggesting a beneficial role of MPP and TPE in the treatment of ARDS secondary to scrub typhus infection. To our knowledge, this is the first case report regarding the use of MPP therapy and TPE in a patient with ARDS due to scrub typhus infection.
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spelling pubmed-96626972022-11-17 Rapid Recovery of Acute Respiratory Distress Syndrome in Scrub Typhus, With Pulse Methylprednisolone and Therapeutic Plasma Exchange Rathnasekara, Thilina Wijekoon, Lanka Senanayake, Hemal Siribaddana, Sisira Cureus Internal Medicine Acute respiratory distress syndrome (ARDS) is an atypical presentation of scrub typhus infection with associated high morbidity and mortality compared to uncomplicated scrub typhus infection. Here we report an otherwise healthy 41-year-old female patient admitted with moderate ARDS secondary to scrub typhus infection who gained comparatively rapid recovery within 72 hours following intravenous methylprednisolone pulse (MPP) therapy with therapeutic plasma exchange (TPE), suggesting a beneficial role of MPP and TPE in the treatment of ARDS secondary to scrub typhus infection. To our knowledge, this is the first case report regarding the use of MPP therapy and TPE in a patient with ARDS due to scrub typhus infection. Cureus 2022-10-15 /pmc/articles/PMC9662697/ /pubmed/36407237 http://dx.doi.org/10.7759/cureus.30329 Text en Copyright © 2022, Rathnasekara et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Rathnasekara, Thilina
Wijekoon, Lanka
Senanayake, Hemal
Siribaddana, Sisira
Rapid Recovery of Acute Respiratory Distress Syndrome in Scrub Typhus, With Pulse Methylprednisolone and Therapeutic Plasma Exchange
title Rapid Recovery of Acute Respiratory Distress Syndrome in Scrub Typhus, With Pulse Methylprednisolone and Therapeutic Plasma Exchange
title_full Rapid Recovery of Acute Respiratory Distress Syndrome in Scrub Typhus, With Pulse Methylprednisolone and Therapeutic Plasma Exchange
title_fullStr Rapid Recovery of Acute Respiratory Distress Syndrome in Scrub Typhus, With Pulse Methylprednisolone and Therapeutic Plasma Exchange
title_full_unstemmed Rapid Recovery of Acute Respiratory Distress Syndrome in Scrub Typhus, With Pulse Methylprednisolone and Therapeutic Plasma Exchange
title_short Rapid Recovery of Acute Respiratory Distress Syndrome in Scrub Typhus, With Pulse Methylprednisolone and Therapeutic Plasma Exchange
title_sort rapid recovery of acute respiratory distress syndrome in scrub typhus, with pulse methylprednisolone and therapeutic plasma exchange
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662697/
https://www.ncbi.nlm.nih.gov/pubmed/36407237
http://dx.doi.org/10.7759/cureus.30329
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