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Extracellular vesicles from focal segmental glomerulosclerosis pediatric patients induce STAT3 activation and mesangial cell proliferation

INTRODUCTION: Primary focal segmental glomerulosclerosis (FSGS), a major cause of end-stage kidney disease (ESKD) in adolescents and young adults, is attributable to recognized genetic mutations in a minority of cases. For the majority with idiopathic primary FSGS, the cause of the disease is unknow...

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Detalles Bibliográficos
Autores principales: Pekkucuksen, Naile T., Liu, Lauren P., Aly, Rasha, Shoemaker, Lawrence R., Alli, Abdel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662727/
https://www.ncbi.nlm.nih.gov/pubmed/36374911
http://dx.doi.org/10.1371/journal.pone.0274598