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Down-regulation of hepatic expression of GHR/STAT5/IGF-1 signaling pathway fosters development and aggressiveness of HCV-related hepatocellular carcinoma: Crosstalk with Snail-1 and type 2 transforming growth factor-beta receptor

BACKGROUND AND AIMS: So far, few clinical trials are available concerning the role of growth hormone receptor (GHR)/signal transducer and activator of transcription 5 (STAT5)/insulin like growth factor-1 (IGF-1) axis in hepatocarcinogenesis. The aim of this study was to evaluate the hepatic expressi...

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Detalles Bibliográficos
Autores principales:	Abu El-Makarem, Mona A., Kamel, Mariana F., Mohamed, Ahmed A., Ali, Hisham A., Mohamed, Mahmoud R., Mohamed, Alaa El-Deen M., El-Said, Ahmed M., Ameen, Mahmoud G., Hassnine, Alshymaa A., Hassan, Hatem A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662744/ https://www.ncbi.nlm.nih.gov/pubmed/36374927 http://dx.doi.org/10.1371/journal.pone.0277266

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