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Molecular basis of the PIP(2)-dependent regulation of Ca(V)2.2 channel and its modulation by Ca(V) β subunits
High-voltage-activated Ca(2+) (Ca(V)) channels that adjust Ca(2+) influx upon membrane depolarization are differentially regulated by phosphatidylinositol 4,5-bisphosphate (PIP(2)) in an auxiliary Ca(V) β subunit-dependent manner. However, the molecular mechanism by which the β subunits control the...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662827/ https://www.ncbi.nlm.nih.gov/pubmed/36374183 http://dx.doi.org/10.7554/eLife.69500 |