IL6 and CCL18 Mediate Cross-talk between VHL-Deficient Kidney Cells and Macrophages during Development of Renal Cell Carcinoma

Loss of the von Hippel–Lindau (VHL) tumor suppressor gene function accounts for 70% to 80% of all clear-cell renal cell carcinoma (ccRCC) cases, the most prevalent form of RCC. Accumulating evidence has indicated that ccRCC arises from sites of chronic inflammation, yet how ccRCC tumor cells interac...

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Detalles Bibliográficos
Autores principales: Nguyen, Thi-Ngoc, Nguyen-Tran, Hieu-Huy, Chen, Chen-Yun, Hsu, Tien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Tumor Biology and Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662868/
https://www.ncbi.nlm.nih.gov/pubmed/35666812
http://dx.doi.org/10.1158/0008-5472.CAN-21-3749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662868/
https://www.ncbi.nlm.nih.gov/pubmed/35666812
http://dx.doi.org/10.1158/0008-5472.CAN-21-3749

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