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STINGing the immune system: lessons learned through a model of G34-mutant pediatric high-grade glioma
Pediatric high-grade gliomas (pHGGs) are aggressive diseases with poor outcomes. The diverse molecular heterogeneity in these rare tumors and inadequate tumor models have limited the development of effective therapies. In this issue of the JCI, Haase et al. produced a genetically engineered mouse mo...
Autores principales: | Hall, Connor P., Cronk, James C., Rubens, Jeffrey A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663148/ https://www.ncbi.nlm.nih.gov/pubmed/36377657 http://dx.doi.org/10.1172/JCI164420 |
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