Kappa Free Light Chain Biomarkers Are Efficient for the Diagnosis of Multiple Sclerosis: A Large Multicenter Cohort Study

BACKGROUND AND OBJECTIVES: Kappa free light chains (KFLC) seem to efficiently diagnose MS. However, extensive cohort studies are lacking to establish consensus cut-offs, notably to rule out non-MS autoimmune CNS disorders. Our objectives were to (1) determine diagnostic performances of CSF KFLC, KFL...

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Detalles Bibliográficos
Autores principales: Levraut, Michael, Laurent-Chabalier, Sabine, Ayrignac, Xavier, Bigaut, Kévin, Rival, Manon, Squalli, Sanae, Zéphir, Hélène, Alberto, Tifanie, Pekar, Jean-David, Ciron, Jonathan, Biotti, Damien, Puissant-Lubrano, Bénédicte, Camdessanché, Jean-Philippe, Tholance, Yannick, Casez, Olivier, Toussaint, Bertrand, Marion, Jeanne, Moreau, Thibault, Lakomy, Daniela, Thomasset, Audrey, Maillart, Elisabeth, Sterlin, Delphine, Maurousset, Aude, Rocher, Auriane, Laplaud, David Axel, Bigot-Corbel, Edith, Bertho, Pierre-Olivier, Pelletier, Jean, Boucraut, Joseph, Labauge, Pierre, Vincent, Thierry, De Sèze, Jérôme, Jahn, Isabelle, Seitz-Polski, Barbara, Thouvenot, Eric, Lebrun-Frenay, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663206/
https://www.ncbi.nlm.nih.gov/pubmed/36376096
http://dx.doi.org/10.1212/NXI.0000000000200049

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