Ixovex-1, a novel oncolytic E1B-mutated adenovirus

There is a great demand for improved oncolytic viruses that selectively replicate within cancer cells while sparing normal cells. Here, we describe a novel oncolytic adenovirus, Ixovex-1, that obtains a cancer-selective replication phenotype by modulating the level of expression of the different, al...

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Detalles Bibliográficos
Autores principales: Anwar, Mohiemen, Arendt, Maja-Louise, Ramachandran, Mohanraj, Carlsson, Anette, Essand, Magnus, Akusjärvi, Göran, Alusi, Ghasan, Öberg, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663300/
https://www.ncbi.nlm.nih.gov/pubmed/35596069
http://dx.doi.org/10.1038/s41417-022-00480-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663300/
https://www.ncbi.nlm.nih.gov/pubmed/35596069
http://dx.doi.org/10.1038/s41417-022-00480-3

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