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Ixovex-1, a novel oncolytic E1B-mutated adenovirus

There is a great demand for improved oncolytic viruses that selectively replicate within cancer cells while sparing normal cells. Here, we describe a novel oncolytic adenovirus, Ixovex-1, that obtains a cancer-selective replication phenotype by modulating the level of expression of the different, al...

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Detalles Bibliográficos
Autores principales:	Anwar, Mohiemen, Arendt, Maja-Louise, Ramachandran, Mohanraj, Carlsson, Anette, Essand, Magnus, Akusjärvi, Göran, Alusi, Ghasan, Öberg, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663300/ https://www.ncbi.nlm.nih.gov/pubmed/35596069 http://dx.doi.org/10.1038/s41417-022-00480-3

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