CMTM4 is a subunit of the IL-17 receptor and mediates autoimmune pathology

Interleukin-17A (IL-17A) is a key mediator of protective immunity to yeast and bacterial infections but also drives the pathogenesis of several autoimmune diseases, such as psoriasis or psoriatic arthritis. Here we show that the tetra-transmembrane protein CMTM4 is a subunit of the IL-17 receptor (I...

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Detalles Bibliográficos
Autores principales: Knizkova, Daniela, Pribikova, Michaela, Draberova, Helena, Semberova, Tereza, Trivic, Tijana, Synackova, Alzbeta, Ujevic, Andrea, Stefanovic, Jana, Drobek, Ales, Huranova, Martina, Niederlova, Veronika, Tsyklauri, Oksana, Neuwirth, Ales, Tureckova, Jolana, Stepanek, Ondrej, Draber, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663306/
https://www.ncbi.nlm.nih.gov/pubmed/36271145
http://dx.doi.org/10.1038/s41590-022-01325-9

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