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Pentacyclic triterpenes modulate farnesoid X receptor expression in colonic epithelial cells: Implications for colonic secretory function

The nuclear bile acid receptor, farnesoid X receptor (FXR), is an important regulator of intestinal and metabolic function. Previous studies suggest that pentacyclic triterpenes (PCTs), a class of plant-derived bioactive phytochemical, can modulate FXR activity and may therefore offer therapeutic be...

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Detalles Bibliográficos
Autores principales:	Fallon, Ciara M., Smyth, Jessica S., Quach, Andrew, Lajczak-McGinley, Natalia, O’Toole, Aoibhlinn, Barrett, Kim E., Sheridan, Helen, Keely, Stephen J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663526/ https://www.ncbi.nlm.nih.gov/pubmed/36209824 http://dx.doi.org/10.1016/j.jbc.2022.102569

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