Anti-tumor effects of P-LPK-CPT, a peptide-camptothecin conjugate, in colorectal cancer

To explore highly selective targeting molecules of colorectal cancer (CRC) is a challenge. We previously identified a twelve-amino acid peptide (LPKTVSSDMSLN, namely P-LPK) by phage display technique which may specifically binds to CRC cells. Here we show that P-LPK selectively bind to a panel of hu...

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Detalles Bibliográficos
Autores principales: Hou, Lidan, Hou, Yichao, Liang, Yu, Chen, Baiyu, Zhang, Xintian, Wang, Yu, Zhou, Kun, Zhong, Ting, Long, Bohan, Pang, Wenjing, Wang, Lei, Han, Xu, Li, Linjing, Xu, Ci, Gross, Isabelle, Gaiddon, Christian, Fu, Wei, Yao, Han, Meng, Xiangjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663589/
https://www.ncbi.nlm.nih.gov/pubmed/36376440
http://dx.doi.org/10.1038/s42003-022-04191-1

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