Targeting glutamine metabolism in hepatic stellate cells alleviates liver fibrosis

Glutamine metabolism plays an essential role in cell growth, and glutamate dehydrogenase (GDH) is a key enzyme. GDH promotes the metabolism of glutamate and glutamine to generate ATP, which is profoundly increased in multiple human cancers. Through in vitro and in vivo experiments, we verified that...

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Detalles Bibliográficos
Autores principales: Yin, Xiaochun, Peng, Jin, Gu, Lihong, Liu, Yan, Li, Xihan, Wu, Jinhui, Xu, Bing, Zhuge, Yuzheng, Zhang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663710/
https://www.ncbi.nlm.nih.gov/pubmed/36376267
http://dx.doi.org/10.1038/s41419-022-05409-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663710/
https://www.ncbi.nlm.nih.gov/pubmed/36376267
http://dx.doi.org/10.1038/s41419-022-05409-0

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