Dual roles and evolutionary implications of P26/poxin in antagonizing intracellular cGAS-STING and extracellular melanization immunity

P26, a homolog of the viral-encoded nuclease poxin that neutralizes the cGAS-STING innate immunity, is widely distributed in various invertebrate viruses, lepidopteran insects, and parasitoid wasps. P26/poxin from certain insect viruses also retains protease activity, though its biological role rema...

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Detalles Bibliográficos
Autores principales: Yin, Mengyi, Kuang, Wenhua, Wang, Qianran, Wang, Xi, Yuan, Chuanfei, Lin, Zhe, Zhang, Huanyu, Deng, Fei, Jiang, Haobo, Gong, Peng, Zou, Zhen, Hu, Zhihong, Wang, Manli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663721/
https://www.ncbi.nlm.nih.gov/pubmed/36376305
http://dx.doi.org/10.1038/s41467-022-34761-0

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