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β-sitosterol inhibits trimethylamine production by regulating the gut microbiota and attenuates atherosclerosis in ApoE(–/–) mice

The intestinal microbial metabolite trimethylamine (TMA), which is activated by flavin monooxygenase (FMO) to produce trimethylamine-N-oxide (TMAO), has been implicated in the pathogenesis of atherosclerosis (AS), leading to the development of therapeutic strategies for AS. This study aimed to inves...

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Detalles Bibliográficos
Autores principales:	Wu, Weiping, Liu, Wugao, Wang, Huafu, Wang, Wei, Chu, Weihua, Jin, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663806/ https://www.ncbi.nlm.nih.gov/pubmed/36386330 http://dx.doi.org/10.3389/fcvm.2022.986905

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