Streptolysin S targets the sodium-bicarbonate cotransporter NBCn1 to induce inflammation and cytotoxicity in human keratinocytes during Group A Streptococcal infection

Group A Streptococcus (GAS, Streptococcus pyogenes) is a Gram-positive human pathogen that employs several secreted and surface-bound virulence factors to manipulate its environment, allowing it to cause a variety of disease outcomes. One such virulence factor is Streptolysin S (SLS), a ribosomally-...

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Detalles Bibliográficos
Autores principales: Hammers, Daniel E., Donahue, Deborah L., Tucker, Zachary D., Ashfeld, Brandon L., Ploplis, Victoria A., Castellino, Francis J., Lee, Shaun W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663810/
https://www.ncbi.nlm.nih.gov/pubmed/36389147
http://dx.doi.org/10.3389/fcimb.2022.1002230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663810/
https://www.ncbi.nlm.nih.gov/pubmed/36389147
http://dx.doi.org/10.3389/fcimb.2022.1002230

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