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Ang II acutely stimulates Na,K‐pump in cells from proximal tubules by increasing its phosphorylation at S938 via a PI3K/AKT pathway

Angiotensin II (Ang II)‐dependent stimulation of the AT(1) receptor in proximal tubules increases sodium reabsorption and blood pressure. Reabsorption is driven by the Na,K‐pump that is acutely stimulated by Ang II, which requires phosphorylation of serine‐938 (S938). This site is present in humans...

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Detalles Bibliográficos
Autores principales: Hanna, Fadia S., Alkhouri, Samaa, Rajagopalan, Carthic, Ji, Kyungmin, Mattingly, Raymond R., Yingst, Douglas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663852/
https://www.ncbi.nlm.nih.gov/pubmed/36377055
http://dx.doi.org/10.14814/phy2.15508

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