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Epigenomic landscape study reveals molecular subtypes and EBV-associated regulatory epigenome reprogramming in nasopharyngeal carcinoma

BACKGROUND: Epstein-Barr virus (EBV) latent infection is associated with genome-wide epigenomic changes in several malignancies, but its role in epigenetic dysregulation remains unclear in nasopharyngeal carcinoma (NPC). METHODS: To investigate EBV-associated epigenetic dysregulation, we performed a...

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Detalles Bibliográficos
Autores principales: Ka-Yue Chow, Larry, Lai-Shun Chung, Dittman, Tao, Lihua, Chan, Kui Fat, Tung, Stewart Yuk, Cheong Ngan, Roger Kai, Ng, Wai Tong, Wing-Mui Lee, Anne, Yau, Chun Chung, Lai-Wan Kwong, Dora, Ho-Fun Lee, Victor, Lam, Ka-On, Liu, Jiayan, Chen, Honglin, Dai, Wei, Lung, Maria Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663866/
https://www.ncbi.nlm.nih.gov/pubmed/36371985
http://dx.doi.org/10.1016/j.ebiom.2022.104357