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Clinical outcomes of COVID-19 infection in congenital heart disease: A single-center experience in Indonesia

BACKGROUND: Congenital heart disease (CHD) patients are thought to be vulnerable to COVID-19 complications. In this study, we would like to assess the outcomes and clinical characteristics in COVID-19 CHD patients. METHOD: A single-center, observational study was conducted in National Cardiovascular...

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Autores principales: Siagian, Sisca Natalia, Oetama, Susandy, Pohan, Fathy Zuandi, Mendel, Brian, Lelya, Olfi, Sakti, Damba Dwisepto Aulia, Kurniawati, Yovi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663915/
https://www.ncbi.nlm.nih.gov/pubmed/36386329
http://dx.doi.org/10.3389/fcvm.2022.1022183
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author Siagian, Sisca Natalia
Oetama, Susandy
Pohan, Fathy Zuandi
Mendel, Brian
Lelya, Olfi
Sakti, Damba Dwisepto Aulia
Kurniawati, Yovi
author_facet Siagian, Sisca Natalia
Oetama, Susandy
Pohan, Fathy Zuandi
Mendel, Brian
Lelya, Olfi
Sakti, Damba Dwisepto Aulia
Kurniawati, Yovi
author_sort Siagian, Sisca Natalia
collection PubMed
description BACKGROUND: Congenital heart disease (CHD) patients are thought to be vulnerable to COVID-19 complications. In this study, we would like to assess the outcomes and clinical characteristics in COVID-19 CHD patients. METHOD: A single-center, observational study was conducted in National Cardiovascular Center Harapan Kita (NCCHK). This study included patients with CHD who were hospitalized for COVID-19. The extracted data were baseline characteristics, clinical findings, supportive examination findings, complications, outcomes, and length of stay of the patients. The data were then analyzed using SPSS 26.0 software. RESULT: Twenty-six patients with CHD and COVID-19 infection were included in our study. There were 24 resolved cases and 2 deaths, four patients experienced complications such as renal insufficiency (1), sepsis (2), and multiorgan failure (1). The median length of stay was 13 days. The most common symptoms experienced by the patients were breathlessness (65.4%), cough (57.7%), and fever (42.3%). CONCLUSION: We observed a relatively mild COVID-19 clinical course despite prior research showing that patients with cardiovascular comorbidities, such as CHD, have a higher case-fatality rate. This could be because of the smaller sample size, non-standardized diagnosis, severity, treatment, and age group.
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spelling pubmed-96639152022-11-15 Clinical outcomes of COVID-19 infection in congenital heart disease: A single-center experience in Indonesia Siagian, Sisca Natalia Oetama, Susandy Pohan, Fathy Zuandi Mendel, Brian Lelya, Olfi Sakti, Damba Dwisepto Aulia Kurniawati, Yovi Front Cardiovasc Med Cardiovascular Medicine BACKGROUND: Congenital heart disease (CHD) patients are thought to be vulnerable to COVID-19 complications. In this study, we would like to assess the outcomes and clinical characteristics in COVID-19 CHD patients. METHOD: A single-center, observational study was conducted in National Cardiovascular Center Harapan Kita (NCCHK). This study included patients with CHD who were hospitalized for COVID-19. The extracted data were baseline characteristics, clinical findings, supportive examination findings, complications, outcomes, and length of stay of the patients. The data were then analyzed using SPSS 26.0 software. RESULT: Twenty-six patients with CHD and COVID-19 infection were included in our study. There were 24 resolved cases and 2 deaths, four patients experienced complications such as renal insufficiency (1), sepsis (2), and multiorgan failure (1). The median length of stay was 13 days. The most common symptoms experienced by the patients were breathlessness (65.4%), cough (57.7%), and fever (42.3%). CONCLUSION: We observed a relatively mild COVID-19 clinical course despite prior research showing that patients with cardiovascular comorbidities, such as CHD, have a higher case-fatality rate. This could be because of the smaller sample size, non-standardized diagnosis, severity, treatment, and age group. Frontiers Media S.A. 2022-11-01 /pmc/articles/PMC9663915/ /pubmed/36386329 http://dx.doi.org/10.3389/fcvm.2022.1022183 Text en Copyright © 2022 Siagian, Oetama, Pohan, Mendel, Lelya, Sakti and Kurniawati. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Siagian, Sisca Natalia
Oetama, Susandy
Pohan, Fathy Zuandi
Mendel, Brian
Lelya, Olfi
Sakti, Damba Dwisepto Aulia
Kurniawati, Yovi
Clinical outcomes of COVID-19 infection in congenital heart disease: A single-center experience in Indonesia
title Clinical outcomes of COVID-19 infection in congenital heart disease: A single-center experience in Indonesia
title_full Clinical outcomes of COVID-19 infection in congenital heart disease: A single-center experience in Indonesia
title_fullStr Clinical outcomes of COVID-19 infection in congenital heart disease: A single-center experience in Indonesia
title_full_unstemmed Clinical outcomes of COVID-19 infection in congenital heart disease: A single-center experience in Indonesia
title_short Clinical outcomes of COVID-19 infection in congenital heart disease: A single-center experience in Indonesia
title_sort clinical outcomes of covid-19 infection in congenital heart disease: a single-center experience in indonesia
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663915/
https://www.ncbi.nlm.nih.gov/pubmed/36386329
http://dx.doi.org/10.3389/fcvm.2022.1022183
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