New triazole-substituted triterpene derivatives exhibiting anti-RSV activity: synthesis, biological evaluation, and molecular modeling

Respiratory syncytial virus (RSV) is a major cause of acute lower respiratory tract infections in infants. Currently, ribavirin, a nucleoside analog containing a 1,2,4-triazole-3-carboxamide moiety, is a first-line drug for its treatment, however, its clinical use has been limited due to its side ef...

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Detalles Bibliográficos
Autores principales: da Silva, Elenilson F, Antunes Fernandes, Krist Helen, Diedrich, Denise, Gotardi, Jessica, Freire Franco, Marcia Silvana, Tomich de Paula da Silva, Carlos Henrique, Duarte de Souza, Ana Paula, Baggio Gnoatto, Simone Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2022
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663970/
https://www.ncbi.nlm.nih.gov/pubmed/36447520
http://dx.doi.org/10.3762/bjoc.18.161

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