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NFATc1 signaling drives chronic ER stress responses to promote NAFLD progression

OBJECTIVES: Non-alcoholic fatty liver disease (NAFLD) can persist in the stage of simple hepatic steatosis or progress to steatohepatitis (NASH) with an increased risk for cirrhosis and cancer. We examined the mechanisms controlling the progression to severe NASH in order to develop future treatment...

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Detalles Bibliográficos
Autores principales:	Latif, Muhammad Umair, Schmidt, Geske Elisabeth, Mercan, Sercan, Rahman, Raza, Gibhardt, Christine Silvia, Stejerean-Todoran, Ioana, Reutlinger, Kristina, Hessmann, Elisabeth, Singh, Shiv K, Moeed, Abdul, Rehman, Abdul, Butt, Umer Javed, Bohnenberger, Hanibal, Stroebel, Philipp, Bremer, Sebastian Christopher, Neesse, Albrecht, Bogeski, Ivan, Ellenrieder, Volker
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Hepatology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664107/ https://www.ncbi.nlm.nih.gov/pubmed/35365570 http://dx.doi.org/10.1136/gutjnl-2021-325013

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