Stimulatory MAIT cell antigens reach the circulation and are efficiently metabolised and presented by human liver cells

OBJECTIVE: Mucosal-associated invariant T (MAIT) cells are the most abundant T cells in human liver. They respond to bacterial metabolites presented by major histocompatibility complex-like molecule MR1. MAIT cells exert regulatory and antimicrobial functions and are implicated in liver fibrogenesis...

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Detalles Bibliográficos
Autores principales: Lett, Martin J, Mehta, Hema, Keogh, Adrian, Jaeger, Tina, Jacquet, Maxime, Powell, Kate, Meier, Marie-Anne, Fofana, Isabel, Melhem, Hassan, Vosbeck, Jürg, Cathomas, Gieri, Heigl, Andres, Heim, Markus H, Burri, Emanuel, Mertz, Kirsten D, Niess, Jan Hendrik, Kollmar, Otto, Zech, Christoph J, Ivanek, Robert, Duthaler, Urs, Klenerman, Paul, Stroka, Deborah, Filipowicz Sinnreich, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664123/
https://www.ncbi.nlm.nih.gov/pubmed/35058274
http://dx.doi.org/10.1136/gutjnl-2021-324478

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