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A New View of Activating Mutations in Cancer
A vast effort has been invested in the identification of driver mutations of cancer. However, recent studies and observations call into question whether the activating mutations or the signal strength are the major determinant of tumor development. The data argue that signal strength determines cell...
Autores principales: | Nussinov, Ruth, Tsai, Chung-Jung, Jang, Hyunbum |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664134/ https://www.ncbi.nlm.nih.gov/pubmed/36069825 http://dx.doi.org/10.1158/0008-5472.CAN-22-2125 |
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