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A New View of Activating Mutations in Cancer

A vast effort has been invested in the identification of driver mutations of cancer. However, recent studies and observations call into question whether the activating mutations or the signal strength are the major determinant of tumor development. The data argue that signal strength determines cell...

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Detalles Bibliográficos
Autores principales: Nussinov, Ruth, Tsai, Chung-Jung, Jang, Hyunbum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664134/
https://www.ncbi.nlm.nih.gov/pubmed/36069825
http://dx.doi.org/10.1158/0008-5472.CAN-22-2125

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