Cargando…

Triggering receptor expressed on myeloid cells 2 deficiency exacerbates injury-induced inflammation in a mouse model of tauopathy

Traumatic brain injury (TBI) promotes several Alzheimer’s disease-like pathological features, including microtubule-associated protein tau (MAPT) accumulation within neurons. Macrophage activation in the injured hTau mouse model of tauopathy raises the question whether there is a relationship betwee...

Descripción completa

Detalles Bibliográficos
Autores principales:	Katsumoto, Atsuko, Kokiko-Cochran, Olga N., Bemiller, Shane M., Xu, Guixiang, Ransohoff, Richard M., Lamb, Bruce T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664165/ https://www.ncbi.nlm.nih.gov/pubmed/36389767 http://dx.doi.org/10.3389/fimmu.2022.978423

Ejemplares similares

TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy
por: Bemiller, Shane M., et al.
Publicado: (2017)

Ccr2 deletion dissociates cavity size and tau pathology after mild traumatic brain injury
por: Gyoneva, Stefka, et al.
Publicado: (2015)

Genetically enhancing the expression of chemokine domain of CX(3)CL1 fails to prevent tau pathology in mouse models of tauopathy
por: Bemiller, Shane M., et al.
Publicado: (2018)

Loss of tau rescues inflammation-mediated neurodegeneration
por: Maphis, Nicole, et al.
Publicado: (2015)

Laquinimod attenuates inflammation by modulating macrophage functions in traumatic brain injury mouse model
por: Katsumoto, Atsuko, et al.
Publicado: (2018)

Inflammation as a central mechanism in Alzheimer's disease
por: Kinney, Jefferson W., et al.
Publicado: (2018)

TREM2 deficiency eliminates TREM2(+) inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models
por: Jay, Taylor R., et al.
Publicado: (2015)

Selective suppression of the α isoform of p38 MAPK rescues late-stage tau pathology
por: Maphis, Nicole, et al.
Publicado: (2016)

A Tilted Axis: Maladaptive Inflammation and HPA Axis Dysfunction Contribute to Consequences of TBI
por: Tapp, Zoe M., et al.
Publicado: (2019)

Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model
por: Tagge, Chad A, et al.
Publicado: (2018)

What triggers tauopathy in chronic traumatic encephalopathy?
por: Chen, Liam
Publicado: (2018)

The Trem2 R47H variant confers loss-of-function-like phenotypes in Alzheimer’s disease
por: Cheng-Hathaway, Paul J., et al.
Publicado: (2018)

Metformin promotes tau aggregation and exacerbates abnormal behavior in a mouse model of tauopathy
por: Barini, Erica, et al.
Publicado: (2016)

A Levee to the Flood: Pre-injury Neuroinflammation and Immune Stress Influence Traumatic Brain Injury Outcome
por: Houle, Samuel, et al.
Publicado: (2022)

Reduction of the RNA Binding Protein TIA1 Exacerbates Neuroinflammation in Tauopathy
por: LeBlang, Chelsey Jenna, et al.
Publicado: (2020)

The Inflammatory Continuum of Traumatic Brain Injury and Alzheimer’s Disease
por: Kokiko-Cochran, Olga N., et al.
Publicado: (2018)

Glucose deficit triggers tau pathology and synaptic dysfunction in a tauopathy mouse model
por: Lauretti, E, et al.
Publicado: (2017)

Microglia in Alzheimer's Disease: Risk Factors and Inflammation
por: Katsumoto, Atsuko, et al.
Publicado: (2018)

Whole Genome Expression Analysis in a Mouse Model of Tauopathy Identifies MECP2 as a Possible Regulator of Tau Pathology
por: Maphis, Nicole M., et al.
Publicado: (2017)

Progranulin deficiency in Iba-1(+) myeloid cells exacerbates choroidal neovascularization by perturbation of lysosomal function and abnormal inflammation
por: Takahashi, Kei, et al.
Publicado: (2021)

Peripheral administration of tau aggregates triggers intracerebral tauopathy in transgenic mice
por: Clavaguera, Florence, et al.
Publicado: (2013)

Retromer deficiency in Tauopathy models enhances the truncation and toxicity of Tau
por: Asadzadeh, Jamshid, et al.
Publicado: (2022)

TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy
por: Leyns, Cheryl E. G., et al.
Publicado: (2017)

Salmonella enterica serovar Typhimurium ΔmsbB Triggers Exacerbated Inflammation in Nod2 Deficient Mice
por: Claes, Anne-Kathrin, et al.
Publicado: (2014)

Tauopathy in basal ganglia involvement is exacerbated in a subset of patients with Alzheimer's disease: The Hisayama study
por: Hamasaki, Hideomi, et al.
Publicado: (2019)

Astrocytes in Tauopathies
por: Reid, Matthew J., et al.
Publicado: (2020)

Myeloid β-Catenin Deficiency Exacerbates Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice
por: Wang, Fang, et al.
Publicado: (2018)

Heritability in frontotemporal tauopathies
por: Forrest, Shelley L., et al.
Publicado: (2019)

Transmission and spreading of tauopathy in transgenic mouse brain
por: Clavaguera, Florence, et al.
Publicado: (2009)

Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling
por: Gunner, Georgia, et al.
Publicado: (2019)

Microglial Hemoxygenase-1 Deletion Reduces Inflammation in the Retina of Old Mice with Tauopathy
por: Fernández-Albarral, José A., et al.
Publicado: (2022)

Cannabinoid receptor 2 deficiency exacerbates inflammation and neutrophil recruitment
por: Kapellos, Theodore S., et al.
Publicado: (2019)

Interleukin-10 deficiency exacerbates inflammation-induced tau pathology
por: Weston, Lea L., et al.
Publicado: (2021)

Glial contributions to neurodegeneration in tauopathies
por: Leyns, Cheryl E. G., et al.
Publicado: (2017)

Clinical Spectrum of Tauopathies
por: Olfati, Nahid, et al.
Publicado: (2022)

Deficiency in the transcription factor NRF2 worsens inflammatory parameters in a mouse model with combined tauopathy and amyloidopathy
por: Rojo, Ana I., et al.
Publicado: (2018)

Centrality of Myeloid-Lineage Phagocytes in Particle-Triggered Inflammation and Autoimmunity
por: Favor, Olivia K., et al.
Publicado: (2021)

Tau Oligomers Associate with Inflammation in the Brain and Retina of Tauopathy Mice and in Neurodegenerative Diseases
por: Nilson, Ashley N., et al.
Publicado: (2016)

Impact of nutrition on inflammation, tauopathy, and behavioral outcomes from chronic traumatic encephalopathy
por: Yu, Jin, et al.
Publicado: (2018)

Increasing Tau 4R Tau Levels Exacerbates Hippocampal Tau Hyperphosphorylation in the hTau Model of Tauopathy but Also Tau Dephosphorylation Following Acute Systemic Inflammation
por: Barron, Matthew R., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5257q1c5ip04c5g99t9rp94r4r