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Cell-intrinsic differences between human airway epithelial cells from children and adults

The airway epithelium is a protective barrier that is maintained by the self-renewal and differentiation of basal stem cells. Increasing age is a principle risk factor for chronic lung diseases, but few studies have explored age-related molecular or functional changes in the airway epithelium. We re...

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Detalles Bibliográficos
Autores principales: Maughan, Elizabeth F., Hynds, Robert E., Pennycuick, Adam, Nigro, Ersilia, Gowers, Kate H.C., Denais, Celine, Gómez-López, Sandra, Lazarus, Kyren A., Orr, Jessica C., Pearce, David R., Clarke, Sarah E., Lee, Dani Do Hyang, Woodall, Maximillian N.J., Masonou, Tereza, Case, Katie-Marie, Teixeira, Vitor H., Hartley, Benjamin E., Hewitt, Richard J., Al Yaghchi, Chadwan, Sandhu, Gurpreet S., Birchall, Martin A., O’Callaghan, Christopher, Smith, Claire M., De Coppi, Paolo, Butler, Colin R., Janes, Sam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664344/
https://www.ncbi.nlm.nih.gov/pubmed/36388965
http://dx.doi.org/10.1016/j.isci.2022.105409