Cargando…

Stress signaler p38 mitogen-activated kinase activation: a cause for concern?

Oxidative stress (OS) induced activation of p38 mitogen-activated kinase (MAPK) and cell fate from p38 signaling was tested using the human fetal membrane’s amnion epithelial cells (AEC). We created p38 KO AEC using the CRISPR/Cas9 approach and tested cell fate in response to OS on an AEC-free fetal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Radnaa, Enkhtuya, Richardson, Lauren, Goldman, Brett, Burks, Jared K., Baljinnyam, Tuvshintugs, Vora, Natasha, Zhang, Hui-juan, Bonney, Elizabeth A., Han, Arum, Menon, Ramkumar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2022
Materias:	Aging
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664350/ https://www.ncbi.nlm.nih.gov/pubmed/36250628 http://dx.doi.org/10.1042/CS20220491

Ejemplares similares

Microfluidic technology and simulation models in studying pharmacokinetics during pregnancy
por: Kammala, Ananth K., et al.
Publicado: (2023)

Development of a mouse model of ascending infection and preterm birth
por: Spencer, Nicholas R., et al.
Publicado: (2021)

Exosomes from Ureaplasma parvum-infected ectocervical epithelial cells promote feto-maternal interface inflammation but are insufficient to cause preterm delivery
por: Tantengco, Ourlad Alzeus G., et al.
Publicado: (2022)

Testing of drugs using human feto-maternal interface organ-on-chips provide insights into pharmacokinetics and efficacy
por: Richardson, Lauren S., et al.
Publicado: (2022)

Fetal Membranes Contribute to Drug Transport across the Feto-Maternal Interface Utilizing the Breast Cancer Resistance Protein (BCRP)
por: Kammala, Ananthkumar, et al.
Publicado: (2022)

Extracellular Vesicles-mediated recombinant IL-10 protects against ascending infection-associated preterm birth by reducing fetal inflammatory response
por: Kammala, Ananth Kumar, et al.
Publicado: (2023)

High molecular weight sodium hyaluronate improves survival of syndecan-1-deficient septic mice by inhibiting neutrophil migration
por: Baljinnyam, Tuvshintugs, et al.
Publicado: (2021)

Characterization of fetal microchimeric immune cells in mouse maternal hearts during physiologic and pathologic pregnancies
por: Lintao, Ryan C. V., et al.
Publicado: (2023)

Sodium Hydrogen Exchanger Regulatory Factor-1 (NHERF1) Regulates Fetal Membrane Inflammation
por: Kammala, Ananth Kumar, et al.
Publicado: (2020)

Exosomal delivery of NF-κB inhibitor delays LPS-induced preterm birth and modulates fetal immune cell profile in mouse models
por: Sheller-Miller, Samantha, et al.
Publicado: (2021)

Organ-On-Chip Technology: The Future of Feto-Maternal Interface Research?
por: Richardson, Lauren, et al.
Publicado: (2020)

Translational Modeling of Psychomotor Function in Normal and AD-Pathological Aging With Special Concerns on the Effects of Social Isolation
por: Castillo-Mariqueo, Lidia, et al.
Publicado: (2021)

Activation of p38 Mitogen-Activated Protein Kinase in Gaucher’s Disease
por: Kitatani, Kazuyuki, et al.
Publicado: (2015)

P38 Mitogen-activated Protein Kinase and Parkinson’s Disease
por: He, Jianying, et al.
Publicado: (2018)

Extracellular vesicles from maternal uterine cells exposed to risk factors cause fetal inflammatory response
por: Shepherd, Megan C., et al.
Publicado: (2021)

Molar loss further exacerbates 2-VO-induced cognitive impairment associated with the activation of p38MAPK/NFκB pathway
por: Lu, Yunping, et al.
Publicado: (2022)

The activation of p38alpha, and not p38beta, mitogen-activated protein kinase is required for ischemic preconditioning
por: Sicard, Pierre, et al.
Publicado: (2010)

Corrigendum: Molar loss further exacerbates 2-VO-induced cognitive impairment associated with the activation of p38MAPK/NFκB pathway
por: Lu, Yunping, et al.
Publicado: (2022)

Redox-dependent dimerization of p38α mitogen-activated protein kinase with mitogen-activated protein kinase kinase 3
por: Bassi, Rekha, et al.
Publicado: (2017)

The Effect of Commercial Activity Tracker Based Physical Activity Intervention on Body Composition and Cardiometabolic Health Among Recent Retirees
por: Leskinen, Tuija, et al.
Publicado: (2021)

Induction of T Cell Senescence by Cytokine Induced Bystander Activation
por: Abbas, Attiya A., et al.
Publicado: (2021)

Molecular basis of arrhythmic substrate in ageing murine peroxisome proliferator-activated receptor γ co-activator deficient hearts modelling mitochondrial dysfunction
por: Edling, Charlotte E., et al.
Publicado: (2019)

The Ratio of the Genome Two Functional Parts Activity as the Prime Cause of Aging
por: Salnikov, Lev, et al.
Publicado: (2020)

Effect of puerarin on action potential and sodium channel activation in human hypertrophic cardiomyocytes
por: Lin, Yu-hui, et al.
Publicado: (2020)

Mifepristone Increases Life Span in Female Drosophila Without Detectable Antibacterial Activity
por: Landis, Gary N., et al.
Publicado: (2022)

IRE-1 endoribonuclease activity declines early in C. elegans adulthood and is not rescued by reduced reproduction
por: De-Souza, Evandro A., et al.
Publicado: (2022)

The case for inhibiting p38 mitogen-activated protein kinase in heart failure
por: Arabacilar, Pelin, et al.
Publicado: (2015)

Inflammasome Activity in Response to Influenza Vaccination Is Maintained in Monocyte-Derived Peripheral Blood Macrophages in Older Adults
por: Crooke, Stephen N., et al.
Publicado: (2021)

Organic Anion Transporting Polypeptide 2B1 in Human Fetal Membranes: A Novel Gatekeeper for Drug Transport During Pregnancy?
por: Ganguly, Esha, et al.
Publicado: (2021)

Conditional deletion of E11/Podoplanin in bone protects against ovariectomy-induced increases in osteoclast formation and activity
por: Staines, Katherine A., et al.
Publicado: (2020)

Randomized Trial: D-Glyceric Acid Activates Mitochondrial Metabolism in 50–60-Year-Old Healthy Humans
por: Hirvonen, O. Petteri, et al.
Publicado: (2021)

Transforming growth factor-β1-regulated Fas/FasL pathway activation suppresses nucleus pulposus cell apoptosis in an inflammatory environment
por: Xie, Jingjing, et al.
Publicado: (2020)

Anthracycline-induced cardiotoxicity and senescence
por: Booth, Laura K., et al.
Publicado: (2022)

p38γ and p38δ Mitogen Activated Protein Kinases (MAPKs), New Stars in the MAPK Galaxy
por: Escós, Alejandra, et al.
Publicado: (2016)

The p38 mitogen-activated protein kinase signaling cascade in CD4 T cells
por: Dodeller, Francis, et al.
Publicado: (2006)

An Inhibition of p38 Mitogen Activated Protein Kinase Delays the Platelet Storage Lesion
por: Skripchenko, Andrey, et al.
Publicado: (2013)

Safety and efficacy of p38 mitogen-activated protein kinase inhibitors (MAPKIs) in COPD
por: Yu, Haichuan, et al.
Publicado: (2022)

Associations between patterns of physical activity, pain intensity, and interference among older adults with chronic pain: a secondary analysis of two randomized controlled trials
por: Fanning, Jason, et al.
Publicado: (2023)

Activation of p38 Mitogen-Activated Protein Kinase Promotes Epidermal Growth Factor Receptor Internalization
por: Vergarajauregui, Silvia, et al.
Publicado: (2006)

Lysosomal dysfunction in diabetic cardiomyopathy
por: Kobayashi, Satoru, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_tp5atakeob7v2fvo4kjs9t06sq