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Low-dose lithium supplementation promotes adipose tissue browning and sarco(endo)plasmic reticulum Ca(2+) ATPase uncoupling in muscle

Sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA) uncoupling in skeletal muscle and mitochondrial uncoupling via uncoupling protein 1 (UCP1) in brown/beige adipose tissue are two mechanisms implicated in energy expenditure. Here, we investigated the effects of glycogen synthase kinase 3 (GSK3) inhi...

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Detalles Bibliográficos
Autores principales: Geromella, Mia S., Ryan, Chantal R., Braun, Jessica L., Finch, Michael S., Maddalena, Lucas A., Bagshaw, Olivia, Hockey, Briana L., Moradi, Fereshteh, Fenech, Rachel K., Ryoo, Jisook, Marko, Daniel M., Dhaliwal, Roopan, Sweezey-Munroe, Jake, Hamstra, Sophie I., Gardner, Georgina, Silvera, Sebastian, Vandenboom, Rene, Roy, Brian D., Stuart, Jeffrey A., MacPherson, Rebecca E.K., Fajardo, Val A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664358/
https://www.ncbi.nlm.nih.gov/pubmed/36209826
http://dx.doi.org/10.1016/j.jbc.2022.102568