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Identifying C. elegans lifespan mutants by screening for early-onset protein aggregation

Genetic screens are widely used to identify genes that control specific biological functions. In Caenorhabditis elegans, forward genetic screens rely on the isolation of reproductively active mutants that can self-propagate clonal populations. Screens that target post-reproductive phenotypes, such a...

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Detalles Bibliográficos
Autores principales:	Midkiff, Daniel F., Huayta, Javier, Lichty, James D., Crapster, Joseph P., San-Miguel, Adriana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664360/ https://www.ncbi.nlm.nih.gov/pubmed/36388964 http://dx.doi.org/10.1016/j.isci.2022.105460

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