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Multiple high-regional-incidence cardiac disease diagnosis with deep learning and its potential to elevate cardiologist performance

Currently, due to lack of large-scale datasets containing multiple arrhythmias and acute coronary syndrome-related diseases, AI-aided diagnosis for cardiac diseases is limited in clinical scenarios. Whether AI-based ECG diagnosis can assist cardiologists to improve performance has not been reported....

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Autores principales: Liu, Yunqing, Qin, Chengjin, Liu, Chengliang, Liu, Jinlei, Jin, Yanrui, Li, Zhiyuan, Zhao, Liqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664363/
https://www.ncbi.nlm.nih.gov/pubmed/36388959
http://dx.doi.org/10.1016/j.isci.2022.105434
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author Liu, Yunqing
Qin, Chengjin
Liu, Chengliang
Liu, Jinlei
Jin, Yanrui
Li, Zhiyuan
Zhao, Liqun
author_facet Liu, Yunqing
Qin, Chengjin
Liu, Chengliang
Liu, Jinlei
Jin, Yanrui
Li, Zhiyuan
Zhao, Liqun
author_sort Liu, Yunqing
collection PubMed
description Currently, due to lack of large-scale datasets containing multiple arrhythmias and acute coronary syndrome-related diseases, AI-aided diagnosis for cardiac diseases is limited in clinical scenarios. Whether AI-based ECG diagnosis can assist cardiologists to improve performance has not been reported. We constructed a large-scale dataset containing multiple high-regional-incidence arrhythmias and ACS-related diseases, including 162,622 12-lead ECGs collected between January 2018 and March 2021. We presented a deep learning model for clinical ECG diagnosis of multiple cardiac diseases. Results show that our model for diagnosing 15 cardiac abnormalities achieved 88.216% accuracy, and its average AUC ROC score reached 0.961. On the board-certified re-annotated dataset, its performance surpasses that of cardiologists in non-reference group. Moreover, with aid of labels given by our model, accuracy and efficiency for cardiologist increased by 13.5% and 69.9% than non-reference group. Our approach provides solutions for AI-aided diagnosis systems of cardiac diseases in applications.
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spelling pubmed-96643632022-11-15 Multiple high-regional-incidence cardiac disease diagnosis with deep learning and its potential to elevate cardiologist performance Liu, Yunqing Qin, Chengjin Liu, Chengliang Liu, Jinlei Jin, Yanrui Li, Zhiyuan Zhao, Liqun iScience Article Currently, due to lack of large-scale datasets containing multiple arrhythmias and acute coronary syndrome-related diseases, AI-aided diagnosis for cardiac diseases is limited in clinical scenarios. Whether AI-based ECG diagnosis can assist cardiologists to improve performance has not been reported. We constructed a large-scale dataset containing multiple high-regional-incidence arrhythmias and ACS-related diseases, including 162,622 12-lead ECGs collected between January 2018 and March 2021. We presented a deep learning model for clinical ECG diagnosis of multiple cardiac diseases. Results show that our model for diagnosing 15 cardiac abnormalities achieved 88.216% accuracy, and its average AUC ROC score reached 0.961. On the board-certified re-annotated dataset, its performance surpasses that of cardiologists in non-reference group. Moreover, with aid of labels given by our model, accuracy and efficiency for cardiologist increased by 13.5% and 69.9% than non-reference group. Our approach provides solutions for AI-aided diagnosis systems of cardiac diseases in applications. Elsevier 2022-10-26 /pmc/articles/PMC9664363/ /pubmed/36388959 http://dx.doi.org/10.1016/j.isci.2022.105434 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Liu, Yunqing
Qin, Chengjin
Liu, Chengliang
Liu, Jinlei
Jin, Yanrui
Li, Zhiyuan
Zhao, Liqun
Multiple high-regional-incidence cardiac disease diagnosis with deep learning and its potential to elevate cardiologist performance
title Multiple high-regional-incidence cardiac disease diagnosis with deep learning and its potential to elevate cardiologist performance
title_full Multiple high-regional-incidence cardiac disease diagnosis with deep learning and its potential to elevate cardiologist performance
title_fullStr Multiple high-regional-incidence cardiac disease diagnosis with deep learning and its potential to elevate cardiologist performance
title_full_unstemmed Multiple high-regional-incidence cardiac disease diagnosis with deep learning and its potential to elevate cardiologist performance
title_short Multiple high-regional-incidence cardiac disease diagnosis with deep learning and its potential to elevate cardiologist performance
title_sort multiple high-regional-incidence cardiac disease diagnosis with deep learning and its potential to elevate cardiologist performance
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664363/
https://www.ncbi.nlm.nih.gov/pubmed/36388959
http://dx.doi.org/10.1016/j.isci.2022.105434
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