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Protocol for using GRPath to identify putative gene regulation paths in complex human diseases

Unfolding the “black-box” associations between genotype and phenotype is essential for understanding the molecular mechanisms of complex human diseases. Here, we describe the use of GRPath to uncover putative causal paths (pcPaths) from genetic variants to disease phenotypes. GRPath takes multiple o...

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Detalles Bibliográficos
Autores principales:	Xi, Xi, Li, Haochen, Wei, Lei, Zhang, Xuegong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664398/ https://www.ncbi.nlm.nih.gov/pubmed/36386883 http://dx.doi.org/10.1016/j.xpro.2022.101831

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