CRIT: Identifying RNA-binding protein regulator in circRNA life cycle via non-negative matrix factorization

Circular RNAs (circRNAs) are endogenous non-coding RNAs that regulate gene expression and participate in carcinogenesis. However, the RNA-binding proteins (RBPs) involved in circRNAs biogenesis and modulation remain largely unclear. We developed the circRNA regulator identification tool (CRIT), a no...

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Detalles Bibliográficos
Autores principales: Shao, Mengting, Hao, Shijia, Jiang, Leiming, Cai, Yujie, Zhao, Xing, Chen, Qiuyang, Gao, Xuefei, Xu, Jianzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664520/
https://www.ncbi.nlm.nih.gov/pubmed/36420213
http://dx.doi.org/10.1016/j.omtn.2022.10.015

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