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A complex case of necrobiotic xanthogranuloma with IgG‐kappa paraproteinemia: Disease regression achieved with melphalan and prednisone combination therapy

Necrobiotic xanthogranuloma (NXG) is a rare dermatosis that is often associated with monoclonal paraproteinemia and hematological malignancies. We report the rare case of an 84‐year‐old gentleman with extensive truncal NXG and IgG‐kappa paraproteinemia who achieved significant disease regression fol...

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Detalles Bibliográficos
Autores principales: Malherbe, Jacques A. J., Cooney, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664537/
https://www.ncbi.nlm.nih.gov/pubmed/36397850
http://dx.doi.org/10.1002/ccr3.6554
Descripción
Sumario:Necrobiotic xanthogranuloma (NXG) is a rare dermatosis that is often associated with monoclonal paraproteinemia and hematological malignancies. We report the rare case of an 84‐year‐old gentleman with extensive truncal NXG and IgG‐kappa paraproteinemia who achieved significant disease regression following six cycles of combination melphalan/prednisone therapy.