A complex case of necrobiotic xanthogranuloma with IgG‐kappa paraproteinemia: Disease regression achieved with melphalan and prednisone combination therapy

Necrobiotic xanthogranuloma (NXG) is a rare dermatosis that is often associated with monoclonal paraproteinemia and hematological malignancies. We report the rare case of an 84‐year‐old gentleman with extensive truncal NXG and IgG‐kappa paraproteinemia who achieved significant disease regression fol...

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Detalles Bibliográficos
Autores principales: Malherbe, Jacques A. J., Cooney, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664537/
https://www.ncbi.nlm.nih.gov/pubmed/36397850
http://dx.doi.org/10.1002/ccr3.6554
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author Malherbe, Jacques A. J.
Cooney, Julian
author_facet Malherbe, Jacques A. J.
Cooney, Julian
author_sort Malherbe, Jacques A. J.
collection PubMed
description Necrobiotic xanthogranuloma (NXG) is a rare dermatosis that is often associated with monoclonal paraproteinemia and hematological malignancies. We report the rare case of an 84‐year‐old gentleman with extensive truncal NXG and IgG‐kappa paraproteinemia who achieved significant disease regression following six cycles of combination melphalan/prednisone therapy.
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spelling pubmed-96645372022-11-16 A complex case of necrobiotic xanthogranuloma with IgG‐kappa paraproteinemia: Disease regression achieved with melphalan and prednisone combination therapy Malherbe, Jacques A. J. Cooney, Julian Clin Case Rep Case Report Necrobiotic xanthogranuloma (NXG) is a rare dermatosis that is often associated with monoclonal paraproteinemia and hematological malignancies. We report the rare case of an 84‐year‐old gentleman with extensive truncal NXG and IgG‐kappa paraproteinemia who achieved significant disease regression following six cycles of combination melphalan/prednisone therapy. John Wiley and Sons Inc. 2022-11-15 /pmc/articles/PMC9664537/ /pubmed/36397850 http://dx.doi.org/10.1002/ccr3.6554 Text en © 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Malherbe, Jacques A. J.
Cooney, Julian
A complex case of necrobiotic xanthogranuloma with IgG‐kappa paraproteinemia: Disease regression achieved with melphalan and prednisone combination therapy
title A complex case of necrobiotic xanthogranuloma with IgG‐kappa paraproteinemia: Disease regression achieved with melphalan and prednisone combination therapy
title_full A complex case of necrobiotic xanthogranuloma with IgG‐kappa paraproteinemia: Disease regression achieved with melphalan and prednisone combination therapy
title_fullStr A complex case of necrobiotic xanthogranuloma with IgG‐kappa paraproteinemia: Disease regression achieved with melphalan and prednisone combination therapy
title_full_unstemmed A complex case of necrobiotic xanthogranuloma with IgG‐kappa paraproteinemia: Disease regression achieved with melphalan and prednisone combination therapy
title_short A complex case of necrobiotic xanthogranuloma with IgG‐kappa paraproteinemia: Disease regression achieved with melphalan and prednisone combination therapy
title_sort complex case of necrobiotic xanthogranuloma with igg‐kappa paraproteinemia: disease regression achieved with melphalan and prednisone combination therapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664537/
https://www.ncbi.nlm.nih.gov/pubmed/36397850
http://dx.doi.org/10.1002/ccr3.6554
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