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Black carbon content in airway macrophages is associated with increased severe exacerbations and worse COPD morbidity in SPIROMICS

BACKGROUND: Airway macrophages (AM), crucial for the immune response in chronic obstructive pulmonary disease (COPD), are exposed to environmental particulate matter (PM), which they retain in their cytoplasm as black carbon (BC). However, whether AM BC accurately reflects environmental PM(2.5) expo...

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Detalles Bibliográficos
Autores principales:	Tejwani, Vickram, Woo, Han, Liu, Chen, Tillery, Anna K., Gassett, Amanda J., Kanner, Richard E., Hoffman, Eric A., Martinez, Fernando J., Woodruff, Prescott G., Barr, R. Graham, Fawzy, Ashraf, Koehler, Kirsten, Curtis, Jeffrey L., Freeman, Christine M., Cooper, Christopher B., Comellas, Alejandro P., Pirozzi, Cheryl, Paine, Robert, Tashkin, Donald, Krishnan, Jerry A., Sack, Coralynn, Putcha, Nirupama, Paulin, Laura M., Zusman, Marina, Kaufman, Joel D., Alexis, Neil E., Hansel, Nadia N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664618/ https://www.ncbi.nlm.nih.gov/pubmed/36376879 http://dx.doi.org/10.1186/s12931-022-02225-0

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