New strategy for antimetastatic treatment of lung cancer: a hypothesis based on circulating tumour cells

Metastasis is the primary cause of death in lung cancer patients. However, until now, effective drugs and intervention strategies for treating lung cancer metastasis have been lacking. This hypothesis focuses on circulating tumour cells (CTCs) to develop a new antimetastatic therapeutic strategy for...

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Detalles Bibliográficos
Autores principales: Que, Zujun, Tian, Jianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664634/
https://www.ncbi.nlm.nih.gov/pubmed/36376934
http://dx.doi.org/10.1186/s12935-022-02782-w
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author Que, Zujun
Tian, Jianhui
author_facet Que, Zujun
Tian, Jianhui
author_sort Que, Zujun
collection PubMed
description Metastasis is the primary cause of death in lung cancer patients. However, until now, effective drugs and intervention strategies for treating lung cancer metastasis have been lacking. This hypothesis focuses on circulating tumour cells (CTCs) to develop a new antimetastatic therapeutic strategy for lung cancer. Here, we outline the role of CTCs in tumour metastasis and their functional effects during the treatment of lung cancer patients. Additionally, we hypothesized the possibility of CTCs as a novel biomarker and therapeutic target in preventing and treating metastasis in patients with early-stage lung cancer. We hope that the realization of this hypothesis will improve the overall survival of lung cancer.
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spelling pubmed-96646342022-11-15 New strategy for antimetastatic treatment of lung cancer: a hypothesis based on circulating tumour cells Que, Zujun Tian, Jianhui Cancer Cell Int Hypothesis Metastasis is the primary cause of death in lung cancer patients. However, until now, effective drugs and intervention strategies for treating lung cancer metastasis have been lacking. This hypothesis focuses on circulating tumour cells (CTCs) to develop a new antimetastatic therapeutic strategy for lung cancer. Here, we outline the role of CTCs in tumour metastasis and their functional effects during the treatment of lung cancer patients. Additionally, we hypothesized the possibility of CTCs as a novel biomarker and therapeutic target in preventing and treating metastasis in patients with early-stage lung cancer. We hope that the realization of this hypothesis will improve the overall survival of lung cancer. BioMed Central 2022-11-15 /pmc/articles/PMC9664634/ /pubmed/36376934 http://dx.doi.org/10.1186/s12935-022-02782-w Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Hypothesis
Que, Zujun
Tian, Jianhui
New strategy for antimetastatic treatment of lung cancer: a hypothesis based on circulating tumour cells
title New strategy for antimetastatic treatment of lung cancer: a hypothesis based on circulating tumour cells
title_full New strategy for antimetastatic treatment of lung cancer: a hypothesis based on circulating tumour cells
title_fullStr New strategy for antimetastatic treatment of lung cancer: a hypothesis based on circulating tumour cells
title_full_unstemmed New strategy for antimetastatic treatment of lung cancer: a hypothesis based on circulating tumour cells
title_short New strategy for antimetastatic treatment of lung cancer: a hypothesis based on circulating tumour cells
title_sort new strategy for antimetastatic treatment of lung cancer: a hypothesis based on circulating tumour cells
topic Hypothesis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664634/
https://www.ncbi.nlm.nih.gov/pubmed/36376934
http://dx.doi.org/10.1186/s12935-022-02782-w
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